The Importance of Giving the Right Chemotherapy the First Time
- Pramod Chinder
- Feb 20
- 3 min read

Why Right Chemotherapy Matters More Than Just Giving Chemotherapy
Chemotherapy is the backbone of cancer treatment, but in sarcomas—especially in children—the difference between "giving chemotherapy" and "giving the right chemotherapy" is life-altering. In India, due to a lack of standardized, audited protocols, only 1 in 5 children with sarcoma receives the right chemotherapy. This gap leads to delayed treatments, higher costs, and poor survival outcomes.
At The Yellow Ribbon, our mission is simple: Every sarcoma patient must receive the right chemotherapy the first time—because in oncology, there are no second chances when it comes to selecting the right treatment.
What Defines "Right Chemotherapy" ?
Right chemotherapy is following:
Evidence-based treatment protocols (proven by global research in 2025).
Proper drug combinations tailored to specific sarcoma subtypes.
Correct dosages to maximize tumor destruction.
Strict monitoring to manage toxicity and ensure patient safety.
When chemotherapy is administered correctly, it is highly toxic—not just to cancer cells but also to the patient and the treating doctors. However, this toxicity is necessary to ensure the complete elimination of the tumor.
The Harsh Truth: "Some Chemotherapy" vs. "Right Chemotherapy"
Many hospitals offer "some chemotherapy," meaning:
Patients experience fewer side effects (which may seem like a good thing but means the chemo is not strong enough).
Doctors & hospitals have an easier time managing mild cases with fewer complications.
Tumor cells survive and grow back stronger, leading to treatment failure and reduced survival rates.
On the other hand, right chemotherapy is challenging but essential:
⚠ Toxic to Patients – Causes side effects, but is necessary for cure.
⚠ Toxic to Doctors – Requires expertise, constant monitoring, and an experienced team.
⚠ Toxic to Tumor Cells – Completely eliminates cancer when given at the right dose.
In short, easy chemotherapy is comfortable—but ineffective. Right chemotherapy is hard—but curative.
Case Study: The Cost of Delay
Just last week, we saw a young sarcoma patient from Bengaluru who had been treated at a reputed hospital. The problem? The patient received low-dose, ineffective chemotherapy due to a lack of sarcoma specialization. By the time they reached us, the tumor had grown uncontrollably, leaving fewer treatment options and a poorer prognosis.

This case is not unique. Across India, many patients receive suboptimal sarcoma treatment simply because of misinformation, stigma, or lack of access to specialized centers.
Gold-Standard Chemotherapy for Sarcoma in 2025
For example, in osteosarcoma, the MAP Protocol (Methotrexate, Adriamycin, Cisplatin) is globally recognized as the best chemotherapy regimen. Yet, in India, it is rarely given correctly due to logistical and expertise challenges. The result? Poor survival rates compared to international standards.
At The Yellow Ribbon, we follow globally accepted protocols to ensure every patient gets the treatment they deserve.
How We Are Changing This at The Yellow Ribbon
Multidisciplinary Global Tumor Boards – Every case is reviewed by international experts.
AI-Powered Chemotherapy Tracking – Ensures strict protocol adherence.
Early Diagnosis & Standardized Treatment – Educating families to seek treatment at true sarcoma centers early.
Advocacy & Awareness– Helping patients make informed decisions about where they seek treatment.
Final Takeaway: Choose the Right Chemotherapy First Time
Sarcoma treatment should never be a guessing game. If you or a loved one is diagnosed, demand:
✅ A hospital that follows gold-standard sarcoma protocols.
✅ A team that specializes in sarcoma oncology.
✅ The right chemotherapy—not just any chemotherapy.
The right treatment at the right time saves lives. Let’s work together to ensure no sarcoma patient in India has to suffer due to misinformation or inadequate care.
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